ASCB Rainbow

Subgroup K

Subgroup K: When Cytoskeletal Networks Collide

8:30 am – 12:30 pm, Room 118A
Organizer: Shae B. Padrick, Drexel University, College of Medicine

The eukaryotic cytoskeleton is a collection of multiple filament forming systems including: actin, microtubules, intermediate filaments, and septins. Individual cytoskeleton systems all have powerful self-organization properties, with their signature common feature being the ability to form polymers. These cytoskeletal systems interact with one-another, in both transient and more persistent assemblies.  When cytoskeletal systems interact, distinct cytoskeletal organizations, signaling and dynamic behaviors emerge. Here, we present recent and emerging stories on the functional consequences and the cytoskeletal network organizational changes that occur when cytoskeletal networks collide.


8:30-8:40 am- Introduction. Shae B. Padrick, Drexel University, College of Medicine
8:40-9:15 am- Where the septins meet microtubules: spatial guidance of microtubule organization and interactions with motors. Elias T. Spiliotis, Drexel University
9:15-9:50 am- Role of adenomatouspolyposis coli (APC) at the actin-microtubule intersection during cell migration. Maria Angeles Juanes, Brandeis University
9:50-10:25 am – Nebulette integrates desmin intermediate filaments to cardiac actin. Gloria M. Conover, Texas A&M University
10:25-10:35 am- Coffee break
10:35-11:10 am- Mechanisms regulating intermediate filament transport driven by microtubule-dependent motors. Amelie Robert, Northwestern University, Feinberg School of Medicine
11:10-11:45 am- Septins control of actin nucleation and network shape. Shae B. Padrick, Drexel University, College of Medicine
11:45 am-12:20 pm- Alpha-catenin integrates the actin and intermediate filament cytoskeletons at cardiomyocyte intercellular junctions. Adam Kwiatkowski, University of Pittsburgh School of Medicine
12:20-12:30 pm- Discussion

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