ASCB Rainbow

Subgroup H

Subgroup H: The Cell Biology of Glycoconjugates

8:30 am – 12:30 pm, Room 117
Organizers: Michael Boyce, Duke University; and Richard Steet, University of Georgia

Glycoproteins and glycolipids impact all aspects of cell biology, and dysregulation of their synthesis and turnover underlies the etiologies of many human diseases. Despite this clear biomedical significance, modern glycobiology and cell biology are not yet fully integrated.  This Special Interest Subgroup session features research presentations from leaders in the field on the cell biological roles of glycoconjugates in a wide range of physiological and disease contexts.  The interactive program will offer attendees a window into the world of glycobiology and the diverse roles that glycoconjugates play in cell and developmental biology. The session will benefit cell biologists who want to learn more about how glycobiology informs their research as well as investigators in need of cutting-edge tools to track glycoconjugates and study their functions.


8:30-8:52 am- Novel Glycosylation Required for Dystroglycan Function as an Extracellular Matrix Receptor. Kevin Campbell, University of Iowa
8:52-9:14 am- Dissection of Glycan Function by Mass Spectrometry, Genetic Engineering, and Organotypic Tissue Models. Hans Wandall, University of Copenhagen
9:14-9:36 am- Glycans in Host-Microbe Interactions. Laura Kiessling, Massachusetts Institute of Technology
9:36-9:58 am- Decoding the Genome Using Systems-Approaches. Lara Mahal, New York University
9:58-10:20 am- The Sweeter Side of Cell Signaling. Linda Hsieh-Wilson, California Institute of Technology
10:20-10:42 am- Congenital Disorders of Glycosylation: New Defects, More Challenges.  Hudson Freeze, Sanford Burnham Prebys Medical Discovery Institute
10:42-11:04 am- Protein O-GlcNAcylation in Space and Time. Xiaoyong Yang, Yale University
11:04-11:26 am- Mammalian Cell Adhesion Requires Active Balancing of Nucleotide-Sugar Pools. Michael Boyce, Duke University
11:26-11:46 am- A Sweet Tale of Secretory Granule Biogenesis. Kelly Ten Hagen, National Institute of Dental and Craniofacial Research
11:46 am-12:08 pm- Regulation of Receptor Activity by Carbohydrate-Dependent Lysosomal Targeting. Richard Steet, University of Georgia
12:08-12:30 pm- Concluding questions and discussion

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