ASCB Rainbow

Minisymposium 24

Minisymposium 24: Membrane Shaping by Fusion and Fission

8:30-11:05 am
Room 118B
Co-Chairs: Junjie Hu, Institute of Biophysics, Chinese Academy of Sciences; and Heidi M. McBride, McGill University

8:30 am       Introduction

8:35 am   M239    FUSEXINS, a family of sexual, somatic and viral cell fusion proteins. C. Valansi1, D. Moi2, E. Leikina3, E. Matveev1, M. Graña4, L.V. Chernomordik3, H. Romero5, P.S. Aguilar2, B. Podbilewicz1; 1Biology, Technion- Israel Institute of Technology, Haifa, Israel, 2Laboratorio de Biología Celular de Membranas, Instituto de Investigaciones Biotecnologicas Dr. Rodolfo A. Ugalde (IIB), Buenos Aires, Argentina, 3Section on Membrane Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, 4Unidad de Bioinformática, Institut Pasteur Montevideo, Montevideo, Uruguay, 5Ecología y Evolución, Universidad de la República, Montevideo, Uruguay

8:50 am   M240    Adhesion between membranes is a barrier to membrane fusion. S. Son1, E.M. Schmid1, M.D. Vahey1, M.H. Bakalar1, K. Chan1, D.A. Fletcher1; 1Bioengineering, University of California, Berkeley, Berkeley, CA

9:05 am   M241    Redox-regulated C-terminus of Mitofusins reside within the mitochondrial intermembrane space. H.M. McBride1; 1Neurology and Neurosurgery, McGill University, Montreal, QC

9:20 am   M242    Mitofusin 1-mediated mitochondrial membrane fusion. J. Hu1; 1National Laboratory of Biomacromolecules, Institute of Biophysics, CAS, Beijing, China

9:35 am   M243    Structural Basis of Mitochondrial Receptor Binding and GTP-Driven Conformational Constriction by Dynamin-Related Protein 1. R. Kalia1,2, R.Y. Wang1, A. Yusuf1, P.V. Thomas1, D.A. Agard1, J.M. Shaw2, A. Frost1,2; 1Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, 2Biochemistry, University of Utah, Salt Lake City, UT

9:50 am   M244    Novel roles for Dynamin2 (Dnm2) during ER scission and autophagy. A. Martorell Riera1, M. Iriondo Martinez1, S. Itskanov1, A.M. Van Der Bliek1,2,3; 1Department of Biological Chemistry, University of California Los Angeles, Los Angeles, CA, 2Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA, 3Johnson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA

10:05 am   M245    BAR scaffolds drive membrane fission by locally concentrating intrinsically disordered domains. W.T. Snead1, W.F. Zeno1, G.K. Kago1, E.M. Lafer2, J.C. Stachowiak1; 1Biomedical Engineering, The University of Texas at Austin, Austin, TX, 2Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX

10:20 am   M246    ESCRT membrane scission revealed by optical tweezers. J. Schöneberg 1,2,3, S. Yan1,2,4, A.H. Bahrami3, M. Righini5, I. Lee1,2, M.R. Pavlin2,6, L. Carlson1,2, D.H. Goldman1,2,4, G. Hummer3,7, C. Bustamante1,2,4,5,6,8,9, J.H. Hurley1,2,5,8; 1Molecular and Cell Biology, UC Berkeley, Berkeley, CA, 2California Institute for Quantitative Biosciences, UC Berkeley, Berkeley, CA, 3Theoretical Biophysics, Max Planck Institute of Biophysics, Frankfurt a. M., Germany, 4Howard Hughes Medical Institute, UC Berkeley, Berkeley, CA, 5Department of Chemistry, UC Berkeley, Berkeley, CA, 6Biophysics Graduate Group, UC Berkeley, Berkeley, CA, 7Institute of Biophysics, Goethe University, Frankfurt/M, Germany, 8Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 9Department of Physics, UC Berkeley, Berkeley, CA

10:35 am   M247    Resolving ESCRT-III spirals at the intercellular bridge of dividing cells using 3D STORM imaging. I. Goliand1, T. Dadosh2, N. Elia1; 1Life Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel, 2Faculty of Chemistry, Chemical research support, Weizmann Institute of Science, Rehovot, Israel

10:50 am   M248    Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding. M. Alonso Y Adell1, S. Migliano1, S. Upadhyayula2, Y. Bykov3, J.A. Briggs3, T. Kirchhausen2, D. Teis1; 1Biocenter/Division of Cell Biology, Medical University of Innsbruck, Innsbruck, Austria, 2Department of Cell Biology, Harvard Medical School, Boston, MA, 3Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany

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