ASCB Rainbow

Minisymposium 23

Minisymposium 23: The Life of a Microtubule: Birth, Dynamics and Function

8:30-11:05 am
Room 113B
Co-Chairs: Sabine Petry, Princeton University; and Ram Dixit, Washington University in St Louis

8:30 am       Introduction

8:35 am   M229    The role of GCPs 4, 5, and 6 in microtubule nucleation. D. Farache1, L. Emorine1, L. Haren1, A. Merdes1; 1Centre Biologie Developpement, University Toulouse III / CNRS, Toulouse, France

8:50 am   M230    XMAP215 is a microtubule nucleation factor that functions synergistically with the gamma-tubulin ring complex. S. Petry1, A. Thawani2, R. Kadzik1; 1Molecular Biology, Princeton University, Princeton, NJ, 2Chemical and Biological Engineering, Princeton University, Princeton, NJ

9:05 am   M231    A two-step mechanism for inactivation of MTOC function at the centrosome. J. Magescas1, J.C. Zonka1, J.L. Feldman1; 1Department of Biology, Stanford, Stanford, CA

9:20 am   M232    EB1 and EB3 regulate microtubule minus end organization and Golgi morphology. C. Yang1, J. Wu1, C. Heus 2, I. Grigoriev1, N. Liv2, Y. Yao3, I. Smal3, E. Meijering3, J. Klumperman2, Z. Qi4, A. Akhmanova1; 1Cell Biology, Department of Biology, Utrecht University, Utrecht, Netherlands, 2Department of Cell Biology, University Medical Center Utrecht, Utrecht, Netherlands, 3Departments of Medical Informatics and Radiology, Erasmus University Medical Center, Rotterdam, Netherlands, 4Division of Life Science, The Hong Kong University of Science and Technology, Hong Kong, China

9:35 am   M233    Carboxy-terminal tail of β-tubulin regulates dynamic instability. C.P. Fees1, J.K. Moore1; 1Cell and Development, University of Colorado Anschutz Medical Campus, Aurora, CO

9:50 am   M234    Mechanisms to localize and regulate katanin activity. G.M. Burkart1, R.V. Dixit1; 1Biology, Washington University in St. Louis, St. Louis, MO

10:05 am   M235    Katanin spiral and ring structures shed light on power stroke for microtubule severing. E.A. Zehr1, A. Szyk1, G. Piszczek2, E. Szczesna1, X. Zuo3, A. Roll-Mecak1; 1Cell Biology and Biophysics , NIH, Bethesda, MD, 2Lung and Blood Institute, NIH, Bethesda, MD, 3X-Ray Science Division, Argonne National Laboratory, Argonne, IL

10:20 am   M236    Structure, biochemistry, and activity of a CLASP family TOG. S. Majumdar1, L.M. Rice1; 1Biophysics, UT Southwestern Medical Center, Dallas, TX

10:35 am   M237    Ndc80 complex as an intrinsic regulator of molecular friction at mitotic kinetochores. V.M. Demidov1, S.K. Tripathy1, F.I. Ataullakhanov2, E.L. Grishchuk1; 1Physiology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, 2Center for Theoretical Problems of Physicochemical Pharmacology, Moscow, Russia

10:50 am   M238    Profilin Directly Enhances Microtubule Growth Through Residues Mutated in Amyotrophic Lateral Sclerosis. J.L. Henty-Ridilla1, M.A. Juanes2, B.L. Goode2; 1Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY, 2Cell Biology, Brandeis University, Waltham, MA

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