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Minisymposium 17

Minisymposium 17: Mechanics of Cell Division and Cytokinesis

4:40-7:15 pm
Room 108A
Co-Chairs: Julie Canman*, Columbia University; and Clemens Cabernard, University of Washington

4:40 pm       Introduction

4:45 pm   M169    A myosin-10-wee1 interaction links spindle dynamics to mitotic exit in vertebrate epithelial cells. J.C. Sandquist1, M.E. Larson2,3, S.E. Woolner4, Z. Ding1, W.M. Bement2,3,5; 1Biology, Grinnell College, Grinnell, IA, 2Cellular and Molecular Biology, University of Wisconsin, Madison, WI, 3Laboratory of Cell and Molecular Biology, University of Wisconsin, Madison, WI, 4Division of Developmental Biology and Medicine, University of Manchester, Manchester, United Kingdom, 5Zoology, University of Wisconsin, Madison, WI

5:00 pm   M170    The role of mitotic cell-substrate adhesion remodelling in animal cell division. C.L. Dix1, H.K. Matthews1, S. McLaren1, L. Wolf2, P. Almada1, R. Henriques1, M. Boutros2, B. Baum1; 1Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, United Kingdom, 2Division of Signaling and Functional Genomics, German Cancer Research Center (DKFZ), and Department for Cell and Molecular Biology, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany

5:15 pm   M171    Spindle morphology tailoring through time: Interplay between spindle architecture and morphogenesis of the mammalian brain. D.C. Vargas-Hurtado1, V. Marthiens1, C. Pennetier1, R. Basto1; 1UMR144, Subcellular structure and cellular dynamics, Institut Curie, Paris, France

5:30 pm   M172    Stem Cell Cytokinesis Is Disrupted with Age Due to Diminished Jak/STAT Activity. K. Lenhart1, B. Capozzoli1, S. DiNardo1; 1Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA

5:45 pm   M173    The Aurora kinase A activator TPXL-1 mediates aster-based clearing of contractile ring proteins from the cell poles during cytokinesis. S. Mangal1, T. Kim2, K. Oegema2, E. Zanin1; 1Department Biology II, Ludwig-Maximilians University, Planegg-Martinsried, Germany, 2Department of Cellular and Molecular Medicine, Ludwig Institute for Cancer Research, La Jolla, CA

6:00 pm   M174    Polo-like kinase-1 and Aurora B act in redundant signaling pathways that drive cytokinesis initiation. I.E. Adriaans1, A. Basant2, B. Ponsioen1, M. Glotzer2, S.M. Lens1; 1Center for Molecular Medicine, Molecular Cancer Research, University Medical Center Utrecht, Utrecht, Netherlands, 2Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL

6:15 pm   M175    Structure and constriction mechanism of the actomyosin ring. L.T. Nguyen1,2, G.J. Jensen1,2; 1Biology and Bioengineering, California Institute of Technology, Pasadena, CA, 2Howard Hughes Medical Institute, Chevy Chase, MD

6:30 pm   M176    Modeling contractile ring dynamics in the Caenorhabditis elegans zygote. D.B. Cortes1, S. Ryan1, F. Nedelec2, A.S. Maddox1; 1Biology, University of North Carolina Chapel Hill, Chapel Hill, NC, 2Cell Biology and Biophysics, EMBL Heidelberg, Heidelberg, Germany

6:45 pm   M177    The mechanome of asymmetric cell division. T.T. Pham1,2, J. Helenius3, N. Lee2, E. Lund2, D. Mueller3, C. Cabernard2; 1Biozentrum, University of Basel, Basel , Switzerland, 2Department of Biology, University of Washington, Seattle, WA, 3D-BSSE, ETH Zürich, Basel, Switzerland

*7:00 pm   M178    Cell-intrinsic and extrinsic control of cytokinetic diversity in the C. elegans embryo. T. Davies1, N. Romano Spica1, B. Lesea-Pringle1, J. Dumont2, M.M. Shirasu-Hiza3, J.C. Canman1; 1Pathology and Cell Biology, Columbia University Medical Centre, New York, NY, 2Institut Jacques Monod, Paris, France, 3Genetics, Columbia University Medical Centre, New York, NY

*Julie Canman is the 2017 WICB Junior Awardee for Excellence in Science Research. Her lab’s work will be presented by Tim Davis, a postdoc in her lab.

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