ASCB Rainbow

Microsymposium 18

Microsymposium 18: Bioengineering and Signaling

1:50 pm-3:00 pm
Microsymposia Room 2, Learning Center, Hall C
Moderator: Amanda Haage, University of British Columbia

1:50 pm   E120    Mechanisms connecting the conserved protein kinases Kin1, Pom1, and Ssp1 in fission yeast cell polarity and division. M. Lee1, S.F. Rusin1, N. Jenkins1,2, A.N. Kettenbach1,2, J.B. Moseley11Department of Biochemistry and Cell Biology, The Geisel School of Medicine at Dartmouth, Hanover, NH, 2Norris Cotton Cancer Center, The Geisel School of Medicine at Dartmouth, Lebanon, NH

2:00 pm   E121    Phosphorylation of the HPV E6 oncoprotein by DNA damage response kinases links the E6 interaction with 14-3-3 proteins and p53. J.V. Thatte1, P. Massimi1, L. Banks1; 1Tumour Virology , International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy

2:10 pm   E122    Mad1 promotes tumor progression through destabilization of p53. J. Wan1, B.A. Weaver1; 1Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI

2:20 pm   E123    A novel window for high resolution imaging of the lung reveals mechanisms of metastatic breast cancer progression. L. Borriello1,2, S. Voiculescu3, Y. Wang1,2,4, M.H. Oktay1,4,5, J.S. Condeelis1,2,4, D. Entenberg1,2,4; 1Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY, 2Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY, 3Department of Surgery, Albert Einstein College of Medicine, Bronx, NY, 4Integrated Imaging Program, Albert Einstein College of Medicine, Bronx, NY, 5Department of Pathology, Albert Einstein College of Medicine, Bronx, NY

2:30 pm   E124    Eyes in the cell: Visualizing active kinases using genetically encodable fluorescent biosensors. A. Mukherjee1,2, R. Singh1, S. DilipKumar1, P. Pothula1, S. Udayan1, R. Das3, B. Rao4, A. Gulyani1; 1Technology for the Advancement of Science, Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India, 2School of Chemical and Biotechnology, SASTRA University, Thanjavur, India, 3National Centre for Biological Sciences, Bangalore, India, 4Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, NC

2:40 pm   E125    Investigating the conformational landscape in a protein-signaling complex with optical tweezers. J.P. England1, Y. Hao1, S.S. Taylor2, R.A. Maillard1; 1Chemistry, Georgetown University, Washington, DC, 2Chemistry, University of California San Diego, San Diego, CA

2:50 pm   E126    Three-dimensional modeling of metastatic breast cancer dormancy using tunable PEG-based hydrogels. S. Pradhan1, J.H. Slater1; 1Department of Biomedical Engineering, University of Delaware, Newark, DE

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