ASCB Rainbow

Microsymposium 17

Microsymposium 17: Membrane Dynamics and Trafficking

1:50 pm-3:00 pm
Microsymposia Room 1, Learning Center, Hall C
Moderators: Matthew Akamatsu, University of California, Berkeley; and Brooke Gardner, University of California, Berkeley

1:50 pm   E113    Compartmentalization of plasma membrane by a self-similar cortical actin fractal. S. Sadegh1,2, J.L. Higgins3, P.C. Mannion3, M.M. Tamkun4,5, D. Krapf1,3; 1Electrical and Computer Engineering, Colorado State University, Fort Collis, CO, 2Department of Neurosciences, University of California, San Diego, San Diego, CA, 3School of Biomedical Engineering, Colorado State University, Fort Collins, CO, 4Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, 5Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO

2:00 pm   E114    Signalling via membrane receptors generate functional nanodomains at the plasma membrane of living cells. J. Kalappurakkal1, A.A. Anilkumar1,2, T.S. van Zanten1, M.P. Sheetz3, S. Mayor1,4; 1National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India, 2St. Johns Research Institute, Bangalore, India, 3Mechanobiology Institute, National University of Singapore, Singapore, Singapore, 4Institute for Stem Cell Biology and Regenerative Medicine, Bangalore, India

2:10 pm   E115    The structural basis of an ESCRT-III membrane assembly. H.C. Nguyen1, N. Talledge1,2, J. McCullough2, D.M. Wenzel2, J.J. Skalicky2, W.I. Sundquist2, A. Frost1,2,3; 1Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, 2Department of Biochemistry, University of Utah, Salt Lake City, UT, 3Chan Zuckerberg Biohub, San Francisco, CA

2:20 pm   E116    Architecture of the PI4KIIIα lipid kinase complex. J.A. Lees1, Y. Zhang2, M. Oh1,3,4, C.M. Schauder1, X. Yu5, J. Baskin1,3,4, K. Dobbs6, L.D. Notarangelo6, P. De Camilli1,3,4,7,8, T. Walz2, K.M. Reinisch1; 1Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 2Laboratory of Molecular Electron Microscopy, The Rockefeller University, New York, NY, 3Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT, 4Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT, 5Department of Cell Biology, Harvard Medical School, Boston, MA, 6Immune Deficiency Genetics Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, 7Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 8Kavli Institute for Neuroscience, Yale University School of Medicine, New Haven, CT

2:30 pm   E117    A kinesin-3 motor transports newly synthesized basement membrane proteins specifically to a basal subregion of the lateral plasma membrane in epithelial cells. A.L. Zajac1, A.J. Isabella1,2, K.E. Sy1, S. Horne-Badovinac1; 1Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, 2Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA

2:40 pm   E118    Dynamics of exocyst subunit assembly and vesicle fusion, using CRISPR-edited GFP tagging of endogenous loci. H. Nishida-Fukuda1, I.G. Macara1, S.M. Ahmed1; 1Cell and Developmental Biology, Vanderbilt University, Nashville, TN

2:50 pm   E119    The role of membrane curvature in topography-induced cellular signaling. B. Cui1, W. Zhao1, H. Lou1, F. Santoro1; 1Department of Chemistry, Stanford University, Stanford, CA

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