ASCB Rainbow

Microsymposium 13

Microsymposium 13: Tissue Structure and Cell-Cell Interactions

11:00 am-12:10 pm
Microsymposia Room 1, Learning Center, Hall C
Moderators: Margherita Perillo, Boston College; and Valerie Tutwiler, University of Pennsylvania School of Medicine

11:00 am   E85    Characterization of the mechanically-induced shape change of erythrocytes into polyhedrocytes. V. Tutwiler1, A.R. Mukhitov2, A.D. Peshkova2, G. Le Minh 2, J. Vicksman1, C. Nagaswami1, R.I. Litvinov1, J.W. Weisel1; 1University of Pennsylvania , Philadelphia, PA, 2Kazan Federal Research University , Kazan, Russia

11:10 am   E86    A role for desmosomal cadherins in creating complex tissues. J.A. Broussard1, O. Nekrasova1, J.L. Koetsier2, K.J. Green1; 1Pathology and Dermatology, Northwestern University, Chicago, IL, 2Pathology, Northwestern University, Chicago, IL

11:20 am   E87    Flares of active Rho and F-actin locally reinforce the tight junction barrier in response to mechanical stress. R.E. Stephenson1, T. Higashi1,2, I. Erofeev3, B. Coy1, T.R. Arnold1, A. Goryachev3, A.L. Miller1; 1Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, 2Fukushima Medical University, Fukushima, Japan, 3Centre for Systems Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

11:30 am   E88    A non-canonical Notch signaling complex regulates adherens junctions and endothelial barrier function. M.L. Kutys1,2, W.J. Polacheck1,2, J. Yang1, J. Eyckmans1,2, Y. Wu3, K.K. Hirschi3, C.S. Chen1,2; 1Biomedical Engineering, Boston University, Boston, MA, 2Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 3Cardiovascular Research Center, Yale University, New Haven, CT

11:40 am   E89    Cell-cell adhesion and myosin activity controls the curvature-dependent cortical actin assembly in mammary gland epithelium. W. Jung1, K. Elawad1, S.H. Kang1, Y. Chen1; 1Mechanical Engineering, Johns Hopkins University, Baltimore, MD

11:50 am   E90    Desmosomal regulation of gap junctions via Ras: implications for cardiocutaneous disease. C.Y. Kam1, A.D. Dubash2, F. Sheikh3, P.D. Lampe4, S. Polo5, K.J. Green1,6; 1Department of Pathology, Northwestern University, Chicago, IL, 2Department of Biology, Furman University, Greenville, SC, 3Department of Medicine, University of California-San Diego, La Jolla, CA, 4 Translational Research Program, Fred Hutchinson Cancer Research Center, Seattle, WA, 5FIRC Institute of Molecular Oncology, Milan, Italy, 6Department of Dermatology, Northwestern University, Chicago, IL

12:00 pm   E91    A contractile hoop stress aids in balancing sudden hydrostatic pressure perturbation in a tubular epithelium. D. Maity1, S.X. Sun1,2, Y. Chen2; 1Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 2Mechanical Engineering, Johns Hopkins University, Baltimore, MD

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