ASCB Rainbow


Minisymposium 3

Minisymposium 3: Inside the Nucleus: Genome Organization and Gene Expression

4:15-6:50 pm
Room 115B
Co-Chairs: Trevor K. Archer, National Institute of Environmental Health Sciences, NIH; and Clifford Brangwynne, Princeton University

Supported by The Journal of Cell Biology

4:15 pm       Introduction

4:20 pm   M21    RICC-seq: Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping. V.I. Risca1, S.K. Denny2, A.F. Straight3,4, W.J. Greenleaf1; 1Genetics, Stanford University School of Medicine, Stanford, CA, 2Biophysics, Stanford University, Stanford, CA, 3Biochemistry, Stanford University School of Medicine, Stanford, CA, 4Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA

4:35 pm   M22    Chromatin dependent glucocorticoid receptor plasticity within the genome. J.A. Hoffman1, K.W. Trotter1, T.K. Archer1; 1Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC

4:50 pm   M23    Single-Molecule Analysis of Transcription Factors in the Nucleus of Living Cells. V. Paakinaho1, D.M. Presman1, D.A. Ball1, T.S. Karpova1, E.E. Swinstead1, G.L. Hager1; 1NCI, NIH, Bethesda, MD

5:05 pm   M24    CRISPR-Based DNA Imaging in Living Cells Reveals Cell Cycle-Dependent Chromosome Dynamics. H. Ma1, L. Tu2, A. Naseri3, Y. Chung4, D. Grunwald2, S. Zhang3, T. Pederson1; 1Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, 2RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 3Department of Computer Science, University of Central Florida, Orlando, MA, 4Kavli Institute for the Physics and Mathematics of the Universe, University of Tokyo, Tokyo, Japan

5:20 pm   M25    Interphase chromatin is adaptively folded by ongoing transcription and RNA accumulation. L. Hilbert1,2,3, Y. Sato4, H. Kimura4, F. Julicher2,3, A. Honigmann1, V. Zaburdaev2,3, N. Vastenhouw1; 1Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany, 2Max Planck Institute for the Physics of Complex Systems, Dresden, Germany, 3Center for Systems Biology Dresden, Dresden, Germany, 4Tokyo Institute of Technology, Tokyo, Japan

5:35 pm   M26    Chromatin state contributes to nuclear mechanics. J.F. Johnston1, S. Mochrie2,3, M.C. King1; 1Department of Cell Biology, Yale School of Medicine, New Haven, CT, 2Department of Physics, Yale University, New Haven, CT, 3Department of Applied Physics, Yale University, New Haven, CT

5:50 pm   M27    Lamin A regulates the activity and dynamics of nucleoli. A.L. Buchwalter1, M.W. Hetzer1; 1Molecular and Cell Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA

6:05 pm   M28    Optogenetic control of nuclear body assembly. H. Zhang1, C. Aonbangkhen2, M. Liu1, R. Dilley3, R.A. Greenberg3, D.M. Chenoweth2, M.A. Lampson1; 1Biology, University of Pennsylvania, Philadelphia, PA, 2Chemistry, University of Pennsylvania, Philadelphia, PA, 3Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

6:20 pm   M29    Contribution of Nucleus Size and Cell Size to Genome Activation. C. Hui1, R. Fuentes1, M.C. Mullins1, M.C. Good1,2; 1Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA, 2Bioengineering, University of Pennsylvania, Philadelphia, PA

6:35 pm   M30    Nuclear organogenesis requires nuclear surface area regulation through nucleo-cytoplasmic trafficking. V. Boudreau1,2, J. Hazel3, J. Sellinger1, H.G. Garcia2,4,5, J.F. Allard6, J.C. Gatlin3, P.S. Maddox1; 1Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Physiology Course, Marine Biological Laboratory, Woods Hole, MA, 3Molecular Biology, University of Wyoming, Laramie, WY, 4Molecular  Cell Biology, University of California, Berkeley, Berkeley, CA, 5Physics, University of California, Berkeley, Berkeley, CA, 6Mathematics, University of California, Irvine, Irvine, CA

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