ASCB Rainbow


Minisymposium 14

Minisymposium 14: Autophagy

4:40-7:15 pm
Room 118B
Co-Chairs: Li Yu, Tsinghua University, Beijing, China; and Sascha Martens, Max F. Perutz Laboratories, Austria

4:40 pm       Introduction

4:45 pm   M139    Interplay between ubiquitin and cargo receptors in selective autophagy. S. Martens1; 1Max F Perutz Laboratories, University of Vienna, Vienna, Austria

5:00 pm   M140    The regulation of energy deprivaiton induced autophagy. L. Yu1, Y. Wang1; 1School of Life Sciences, Tsinghua University, Beijing, China

5:15 pm   M141    Autophagosomal closure is mediated by the ESCRT machinery. K. Morita1, I. Koyama-Honda1, Y. Yamashita2, T. Ueno2, E. Morita3, H. Mano2, N. Mizushima1; 1Dept. of Mol. Biol, Grad. Sch. of Med, Univ. of Tokyo, Tokyo, Japan, 2Dept. of Cell. Signal., Grad. Sch. of Med, Univ. of Tokyo, Tokyo, Japan, 3Dept. of Biochem. and Mol. Biol., Fac. of Agric. and Life Sci., Hirosaki Univ., Hirosaki, Japan

5:30 pm   M142    The Autophagy Conjugation Machinery Specifies the Loading of RNA-Binding Proteins into Extracellular Microvesicles. A.M. Leidal1, H.H. Huang2, T. Solvik1, J. Ye1, T. Marsh1, F. Kai3, J. oldsmith1, J.Y. Liu1, A.P. Wiita2, J. Debnath1; 1Pathology, University of California, San Francisco, San Francisco, CA, 2Laboratory Medicine, University of California, San Francisco, San Francisco, CA, 3Surgery, University of California, San Francisco, San Francisco, CA

5:45 pm   M143    Yeast FIT2 homologs mediate the crosstalk between lipid droplet biogenesis, the unfolded protein response and cytoplasmic proteostasis. P.T. Shyu1, W. Gien1, G. Thibault1,2; 1School of Biological Sciences, Nanyang Technological University, Singapore, Singapore, 2Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore

6:00 pm   M144    Compartment-specific regulation of neuronal autophagy during homeostasis and stress. A. Dong1, A. Kulkarni1, V. Kulkarni1, J. Chen1, S. Maday1; 1Neuroscience, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

6:15 pm   M145    The RNA binding protein Zfp106 protects against neurotoxicity caused by C9orf72 GGGGCC repeats. B. Celona1, J. Von Dollen2, S.C. Vatsavayai 3, R. Kashima1, J. Johnson2, A.A. Tang4, A. Hata1, B.L. Miller3, E.J. Huang4, N. Krogan2, W.W. Seeley3,4, B.L. Black1,5; 1Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA, 2Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, 3Neurology, University of California, San Francisco, San Francisco, CA, 4Pathology, University of California, San Francisco, San Francisco, CA, 5Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA

6:30 pm   M146    Ribosome profiling reveals that autophagy impacts DNA damage repair, cell cycle progression and centrosome maintenance through protein translation regulation. J. Goldsmith1, S. Asthana2, T. Marsh1, D. Suresh1, A. Olshen2, J. Debnath1; 1Pathology, University of California, San Francisco, San Francisco, CA, 2Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA

6:45 pm   M147    Post-transcriptional regulation of autophagy. E. Delorme-Axford1, D.J. Klionsky1; 1Life Sciences Institute, University of Michigan, Ann Arbor, MI

7:00 pm   M148    Microvillar sensation of shear stress induces autophagic flux in the intestinal epithelium. S. Kim1,2, J. Ehrman3, M. Ahn4, J. Kondo5, S.W. Crawley6, Y. Oh7, A. Lopez8, J.R. Goldenring9,10, M.J. Tyska1,2, E. Rericha3, K. Lau1,2; 1Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 2Epithelial Biology Center, Vanderbilt University, Nashville, TN, 3Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, 4Department of Food Science and Nutrition, Dong-A University, Busan, Korea, South, 5Department of Biochemistry, Osaka International Cancer Institute, Osaka, Japan, 6Department of Biological Sciences, University of Toledo, Toledo, OH, 7Department of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN, 8Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, TN, 9Department of Surgery, Vanderbilt University, Nashville, TN, 10Nashville VA Medical Center, Nashville, TN

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