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Microsymposium 8

Microsymposium 8: Cytoskeleton and Motility

11:00 am-12:10 pm
Microsymposia Room 2, Learning Center, Hall C
Moderator: Valerie Tutwiler, University of Pennsylvania School of Medicine

11:00 am   E50    Composition of LAT clusters regulates their movement within actomyosin networks. J.A. Ditlev1,2, A.R. Vega3, D.V. Koester2,4, X. Su2,5, R.D. Vale2,5, S. Mayor2,4, K. Jaqaman3, M.K. Rosen1,2; 1Department of Biophysics and Howard Hughes Medical Institute, UT Southwestern Medical Center , Dallas, TX, 2Howard Hughes Medical Institute Summer Institute, Marine Biological Laboratory, Woods Hole, MA, 3Department of Biophysics, UT Southwestern Medical Center, Dallas, TX, 4National Centre for Biological Sciences, Bangalore, India, 5Department of Cellular and Molecular Pharmacology and Howard Hughes Medical Institute, University of California San Francisco, San Francisco, CA

11:10 am   E51    The kinesin-3 KIF1C is a processive dimer and activated by a scaffold phosphatase. A. Bachmann1,2, N. Siddiqui1,2, D. Roth1,2, I. Kaverina3, A. Straube1,2; 1Centre for Mechanochemical Cell Biology, University of Warwick, Coventry, United Kingdom, 2Warwick Medical School, University of Warwick, Coventry, United Kingdom, 3Cell and Developmental Biology, Vanderbilt University, Nashville, TN

11:20 am   E52    Rapid and dynamic arginylation of the leading edge β- actin is required for cell migration. I. Pavlyk1, N.A. Leu1, P. Vedula1, A. Kashina1, S. Kurosaka1; 1Department of Biomedical Sciences, University of Pennsylvania, Philadelphia, PA

11:30 am   E53    Coordination of acto-myosin contractility and mitochondrial positioning during neutrophil migration in live animals. N. Melis1, B. Subramanian1, D. Chen1, C. Parent1, R. Weigert1; 1Laboratory of Cellular and Molecular Biology, National Cancer Institute – NCI, Bethesda, MD

11:40 am   E54    An investigation on the potential of Fidgetin-like 2, a microtubule severing enzyme, as a target to induce angiogenesis and heart regeneration. A.H. Kramer1, V. Paulino2, Y. Wang3, P. Nacharaju1, J.M. Friedman1, B. Zhou3, R. Kitsis2, D.J. Sharp1; 1Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, NY, 2Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Bronx, NY, 3Genetics, Albert Einstein College of Medicine, Bronx, NY

11:50 am   E55    Evolutionarily conserved mechanisms drive sarcomere assembly in cardiomyocytes. A.M. Fenix1, N. Taneja1, M.R. Visetsouk2, B.R. Nixon3, A. Manalo1, J.R. Becker3, S.W. Crawley4, D. Bader1,3, M.J. Tyska1, J.H. Gutzman2, D.T. Burnette1; 1Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, 2Department of Biological Sciences, Cell and Molecular Biology, University of Wisconsin, Milwaukee, WI, 3Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 4Department of Biological Sciences, The University of Toledo, Toledo, OH

12:00 pm   E56    EFHC1 and EFHC2 are necessary for motile cilia function and A-tubule MIP recruitment. B.A. Bayless1, D. Stoddard2,3, Y. Zhao4, J. Gaertig5, D. Nicastro2,3, M. Winey1; 1Molecular and Cellular Biology, University of California, Davis, Davis, CA, 2Biology, Brandeis University, Waltham, MA, 3Cell Biology and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 4Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, 5Cellular Biology, University of Georgia, Athens, GA

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