ASCB Rainbow


Microsymposium 4

Microsymposium 4: Cancer Cell Biology

12:25 pm-1:35 pm
Microsymposia Room 2, Learning Center, Hall C
Moderators: Scott Wilkinson, NIH; and Peter Yu, Ohio State University

12:25 pm   E22    Metastasis by tumor epithelial clusters requires E-cadherin expression. V. Padmanaban1, A.J. Ewald1; 1Departments of Cell Biology and Oncology, Center for Cell Dynamics, Johns Hopkins University School of Medicine, Baltimore, MD

12:35 pm   E23    Leader cells are defined by DNA hypermethylation and aberrant gene expression during collective lung cancer invasion. E.R. Summerbell1,2, J. Bell3,4, J. Konen1,2, J. Kowalski5, P.M. Vertino4, A.I. Marcus2; 1Graduate Program in Cancer Biology, Emory University, Atlanta, GA, 2Department of Hematology and Medical Oncology, Emory University, Atlanta, GA, 3Graduate Program in Genetics and Molecular Biology, Emory University, Atlanta, GA, 4Department of Radiation Oncology, Emory University, Atlanta, GA, 5Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA

12:45 pm   E24    Loss of MTSS1 results in increased metastatic potential in pancreatic cancer. A.E. Zeleniak1,2, W. Huang2,3, M.K. Brinkman2,3, R. Hill2,3; 1Integrated Biomedical Sciences, University of Notre Dame, South Bend, IN, 2Harper Cancer Research Institute, South Bend , IN, 3Biological Sciences, University of Notre Dame, South Bend, IN

12:55 pm   E25    Identification of drivers of chromosome instability in breast tumors. K. Pfister1, J.L. Pipka1, C. Chiang2, R. Clark1, M.J. Guertin1, I. Hall2, T. Stukenberg1; 1Biochemistry and Molecular Genetics, University of Virginia, School of Medicine, Charlottesville, VA, 2McDonnell Genome Institute, Washington University, St. Louis, St Louis , MO

1:05 pm   E26    Prdm14-containing protein complexes regulate chromatin in stem cells, development and cancer. N. Nady1, A. Gupta2, N. Arora1, T. Swigut1, A. Koide2, S. Koide2, J. Wysocka1; 1Department of Chemical and Systems Biology, Stanford University, Stanford, CA, 2Department of Biochemistry and Molecular Pharmacology, New York University, New York, NY

1:15 pm   E27    Analysis of the nature of Paclitaxel resistance in APC knockdown breast cancer cells. B.J. Berkeley1,2,3,4, A.H. Arnason2,3, J.R. Prosperi1,2,3; 1Biochemistry and Molecular Biology, Indiana University School of Medicine, South Bend, IN, 2Biological Sciences, University of Notre Dame, South Bend, IN, 3Harper Cancer Research Institute, South Bend, IN, 4Smurfit Institute of Genetics , Trinity College Dublin, Dublin, Republic of Ireland

1:25 pm   E28    HPV oncoproteins cause specific types of chromosomal instability in head and neck cancer. L.C. Funk1,2,3, D.L. Lee3, P.F. Lambert3,4, R.J. Kimple4,5, B.A. Weaver1,2,3; 1Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 2Molecular and Cellular Pharmacology, University of Wisconsin-Madison, Madison, WI, 3Oncology, University of Wisconsin-Madison, Madison, WI, 4Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, 5Human Oncology, University of Wisconsin-Madison, Madison, WI

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