ASCB Rainbow


Microsymposium 15

Microsymposium 15: Chromosome Structure, Centromeres, and Kinetochores

12:25 pm-1:35 pm
Microsymposia Room 1, Learning Center, Hall C
Moderator: Roberta Sala, Stanford University

12:25 pm   E99    Channel nucleoporins recruit the polo-like kinase PLK-1 to the nuclear pore complexes in prophase to direct nuclear envelope breakdown in C. elegans embryos. L. Martino1, S. Morchoisne-Bolhy2, D.K. Cheerambathur3, L. Van Hove1, J. Dumont4, N. Joly1, A.B. Desai3, V. Doye2, L. Pintard1; 1UMR7592 CNRS – Université Paris Diderot, Sorbonne Paris Cité, Team Cell Cycle and Development, Institut Jacques Monod, Paris, France, 2UMR7592 CNRS – Université Paris Diderot, Sorbonne Paris Cité, Team Non-conventional Functions of Nuclear Pore, Institut Jacques Monod, Paris, France, 3Department of Cellular and Molecular Medicine, University of California, Ludwig Institute for Cancer Research, San Diego, La Jolla, CA, 4UMR7592 CNRS – Université Paris Diderot, Sorbonne Paris Cité, Team Cell Division and Reproduction, Institut Jacques Monod, Paris, France

12:35 pm   E100    Chromosome dynamics simulations reveal the role of condensin and cohesin in building the bottle-brush chromosome architecture. J.G. Lawrimore1,2, A.B. Doshi2, B.S. Friedman2, A. Fulp2, E.Y. Yeh2, K.S. Bloom2;  1Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Biology Department, University of North Carolina at Chapel Hill, Chapel Hill, NC

12:45 pm   E101    The molecular requirements for epigenetic establishment of centromeres depend on the type of underlying DNA. G.A. Logsdon1, C.W. Gambogi1, E.J. Barrey2, P. Heun2, B.E. Black1; 1Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, 2Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom

12:55 pm   E102    Assess the mechanisms that lead to de novo deposition of centromere identity in real time. D. Fachinetti1; 1Department of Cell Biology, Institut Curie, Paris, France

1:05 pm   E103    Dynamically switching protein interaction networks during M-phase progression in vertebrate kinetochores. M. Hara1, T. Hori1, T. Fukagawa1; 1Frontier Biosciences, Osaka University, Osaka, Japan

1:15 pm   E104    Ndc80 complex auto-inhibition is opposed by MIND to increase microtubule binding. E.A. Scarborough1, C.L. Asbury2, T.N. Davis1; 1Biochemistry, University of Washington, Seattle, WA, 2Physiology and Biophysics, University of Washington, Seattle, WA

1:25 pm   E105    Force-dependent changes in the 3D architecture of a kinetochore. E. Roscioli1, C. Smith1, N.J. Burroughs1,2, A. McAinsh1; 1Centre for Mechanochemical Cell Biology, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom, 2Mathematics Institute, University of Warwick, Coventry, United Kingdom

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