ASCB Rainbow


Microsymposium 1

Microsymposium 1: Recent Advances in the Molecular Cell Biology of Neurons

11:00 am-12:10 pm
Microsymposia Room 1, Learning Center, Hall C
Moderators: Gregory Cook, Oklahoma State University – Center for Health Sciences; and Cristian Suarez, University of Chicago

11:00 am   E1    Cytoskeletal regulation of neurodevelopment in a human iPSC-derived autism model. T. Rudisill1, B. Kirk1, C. Johnson1, A. Orbita1, P. Pakala1, H. Dar1, S. Davis1, A.R. Horwitz2, M.J. McConnell3, K.A. Litwa1,2; 1Anatomy and Cell Biology, East Carolina University Brody School of Medicine, Greenville, NC, 2Cell Biology, University of Virginia, Charlottesville, VA, 3Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA

11:10 am   E2    Regulation of axon initial segment cytoskeletal architecture and function by βIV-spectrin. S.L. Jones1, T.M. Svitkina1; 1Biology, University of Pennsylvania, Philadelphia, PA

11:20 am   E3    The microtubule plus-end-tracking protein TACC3 promotes persistent axon outgrowth and mediates responses to axon guidance signals during development. B. Erdogan1, G. Cammarata1, E. Lee1, B. Pratt1, L.A. Lowery1; 1Biology, Boston College, Chestnut Hill, MA

11:30 am   E4    Pharmaco-genetic toolsets for cell-specific subcellular cGMP and calcium manipulation in vivo. O. Ros1, K. Loulier1, S. Ribes1, S. Couvet1, Y. Zagar1, D. Ladarré2, Z. Lenkei2, X. Nicol1; 1Vision Institute, Sorbonne Universités, CNRS, Inserm, Paris, France, 2Brain Plasticity Unit, PSL Research University, ESPCI, CNRS, Paris, France

11:40 am   E5    Mice without c-Abl tyrosine kinase at the CNS show improved learning and memory and increased gene expression of synaptic plasticity. A. Gonzalez1; 1Señalización Celular, Pontificia Universidad Católica de Chile, Santiago de Chile, Chile

11:50 am   E6    Long-term adaptation of G-protein signalling in the brain is facilitated by active G-proteins’ feedback control of the amount of RGS proteins. M.E. Fina1, S.R. Tummala2, N. Vardi1, A. Kashina1, D.W. Dong1,3,4; 1Biomedical Sciences, University of Pennsylvania, Philadelphia, PA, 2Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, 3Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA, 4Department of Neuroscience, University of Pennsylvania, Philadelphia, PA

12:00 pm   E7    Determining the localization and function of schizophrenia-linked protein tSNARE1b in the endolysosomal system of developing neurons. M. Plooster1, G. Rossi2, M.S. Farrell3, P.F. Sullivan3,4, S.L. Gupton2,5,6, P. Brennwald2; 1Cell Biology and Physiology Curriculum, University of North Carolina, Chapel Hill, NC, 2Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 3Department of Genetics, University of North Carolina, Chapel Hill, NC, 4Department of Psychiatry, University of North Carolina, Chapel Hill, NC, 5Neuroscience Center, University of North Carolina, Chapel Hill, NC, 6Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC

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